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Biology · 2016 · May · Paper 2 · HL · Question paper

BiologyQuestion paper2016HLMay

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This question paper is listed under Biology in the 2016 examination archive. Its catalogue level is HL. The catalogue session is May. The information below helps you identify the document before opening the complete PDF. Subject, year and session labels come from the archive catalogue; the original cover remains the reference if a label differs. A file is not automatically suitable for your current syllabus simply because its subject name matches.

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20EP01 20 pages M16/4/BIOLO/HP2/ENG/TZ0/XX Biology Higher level Paper 2 Instructions to candidates • Write your session number in the boxes above. • Do not open this examination paper until instructed to do so. • Section A: answer all questions. • Section B: answer two questions. • Write your answers in the boxes provided. • A calculator is required for this paper. • The maximum mark for this examination paper is [72 marks]. 2 hours 15 minutes © International Baccalaureate Organization 2016 Wednesday 4 May 2016 (morning) 2216 – 6002 [Personal identifier removed] 20EP02 – 2 – M16/4/BIOLO/HP2/ENG/TZ0/XX Section A Answer all questions. Write your answers in the boxes provided. 1. Type I diabetes is a leading cause of death in advanced countries and is associated with various severe or fatal complications, including blindness, kidney failure, heart disease, stroke, neuropathy, and amputations. Embryonic stem cells are considered to be a powerful tool in the treatment of diabetes. In a study, embryonic stem cells were grown in culture and tested for insulin mRNA. A drug was injected into two groups of healthy mice in order to simulate type I diabetes 15 days prior to the transplant of embryonic stem cells. The mice in the transplant group received embryonic stem cells that produce insulin mRNA. The control group did not receive the transplant. The graph shows the blood glucose concentration in both groups. Transplant Blood glucose / mg dL–1 600 500 400 300 200 100 0 –15 –7 0 7 14 21 28 Day Key: control group transplant group [Source: Reprinted from The American Journal of Pathology, Vol 106, no. 6, Takahisa Fujikawa et al., “Teratoma Formation Leads to Failure of Treatment for Type I Diabetes Using Embryonic Stem Cell-Derived Insulin-Producing Cells”, pp. 1781–1791, Copyright © 2005 American Society for Investigative Pathology. Published by Elsevier Inc. All rights reserved.] (a) State the highest mean concentration of blood glucose in the mice with transplants. [1] .......................... mg dL–1 (This question continues on the following page)
File information
Subject
Biology
Document type
Question paper
Year
2016
Session
May
Level
HL
Paper
2
Examination zone
Not labelled in the archive
Language
Not labelled in the archive
File size
1.2 MB
Pages
20
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